BCD

Command-line tools › B

Run bowtie2 from ChatGPT or Claude

Fast and sensitive gapped read aligner. With BCD, ChatGPT, Claude and other AI apps can install and run bowtie2 on your own computer and read what it prints.

Works on

About bowtie2

Version
2.5.5
License
GPL-3.0-or-later
Installs (last 365 days)
1,433 · #2,262 in Homebrew
Homepage
bowtie-bio.sourceforge.net/bowtie2/index.shtml
Install
brew install bowtie2

Try asking

“Install bowtie2 with Homebrew and show me its version”
“Read bowtie2 --help and give me three useful examples for my files”
“Update bowtie2 and tell me what changed”

Questions

Can ChatGPT run bowtie2 on my computer?
Yes. With BCD on your Mac or Linux computer and command permission turned on for it, ChatGPT runs bowtie2 there and reads the output. Claude and other apps with MCP connectors can too.

Do I need to install bowtie2 first?
No. If Homebrew is installed, the AI can run brew install bowtie2 for you.

Is it safe?
A new computer starts read-only: running commands is turned on per computer, and BCD reaches only the folders you allow.

Try it on your computer

BCD connects ChatGPT, Claude and other AI apps to your own Mac, Windows or Linux computer. One computer is free, with 20,000 tool calls a month and no card.

Program data from Homebrew, updated 2026-11-11. Installs are Homebrew's installs on request over the last 365 days.