Run rdkit from ChatGPT or Claude

• MacWorks

  Homebrew has a ready-made build; the AI can install it with brew install rdkit.

• LinuxWorks

  Homebrew on Linux has a ready-made build.

• WindowsNot in Homebrew

  Homebrew does not run on Windows. If rdkit has a Windows build, BCD can run it in PowerShell.

Version

2026.09.2

License

BSD-3-Clause

Installs (last 365 days)

1,131 · #2,532 in Homebrew

Homepage

rdkit.org

Install

brew install rdkit

“Install rdkit with Homebrew and show me its version”
“Read rdkit --help and give me three useful examples for my files”
“Update rdkit and tell me what changed”

boost · boost-python3 · cairo · eigen · freetype · numpy · py3cairo · python@3.15

Can ChatGPT run rdkit on my computer?
Yes. With BCD on your Mac or Linux computer and command permission turned on for it, ChatGPT runs rdkit there and reads the output. Claude and other apps with MCP connectors can too.

Do I need to install rdkit first?
No. If Homebrew is installed, the AI can run brew install rdkit for you.

Is it safe?
A new computer starts read-only: running commands is turned on per computer, and BCD reaches only the folders you allow.

Try it on your computer

BCD connects ChatGPT, Claude and other AI apps to your own Mac, Windows or Linux computer. One computer is free, with 20,000 tool calls a month and no card.