BCD

Command-line tools › S

Run samtools from ChatGPT or Claude

Tools for manipulating next-generation sequencing data. With BCD, ChatGPT, Claude and other AI apps can install and run samtools on your own computer and read what it prints.

Works on

About samtools

Version
1.25
License
MIT
Installs (last 365 days)
4,739 · #1,259 in Homebrew
Homepage
www.htslib.org
Install
brew install samtools

Try asking

“Install samtools with Homebrew and show me its version”
“Read samtools --help and give me three useful examples for my files”
“Update samtools and tell me what changed”

Depends on

htslib

Questions

Can ChatGPT run samtools on my computer?
Yes. With BCD on your Mac or Linux computer and command permission turned on for it, ChatGPT runs samtools there and reads the output. Claude and other apps with MCP connectors can too.

Do I need to install samtools first?
No. If Homebrew is installed, the AI can run brew install samtools for you.

Is it safe?
A new computer starts read-only: running commands is turned on per computer, and BCD reaches only the folders you allow.

Try it on your computer

BCD connects ChatGPT, Claude and other AI apps to your own Mac, Windows or Linux computer. One computer is free, with 20,000 tool calls a month and no card.

Program data from Homebrew, updated 2026-11-11. Installs are Homebrew's installs on request over the last 365 days.